人 TSHR (NM_001142626) cDNA克隆

Accession: NM_001142626
基因名称: TSHR
基因别名: LGR3; CHNG1; hTSHR-I
基因描述: Homo sapiens thyroid stimulating hormone receptor (TSHR), transcript variant 3, mRNA.
种属: Human
CDS区长度: 825 (查看编码区序列)
翻译后氨基酸长度: 274 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 3' UTR and coding sequence and uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus and contains an alternate internal segment compared to isoform 1.
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G108632 人 TSHR (NM_001142626) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]