人 TNFSF13 (NM_001198624) cDNA克隆

基本信息

Accession: NM_001198624
基因名称: TNFSF13
基因别名: APRIL; CD256; TALL2; ZTNF2; TALL-2; TRDL-1; UNQ383/PRO715
基因描述: Homo sapiens tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13), transcript variant eta, mRNA.
种属: Human
CDS区长度: 618 (查看编码区序列)
翻译后氨基酸长度: 205 (查看氨基酸序列)
Transcript Variant: This variant (eta) differs in the 5' UTR, uses a downstream start codon, and lacks an alternate in-frame segment in the 5' coding region, compared to variant alpha, resulting in an isoform (eta) that is shorter than isoform alpha.

订购信息

产品编号 产品名称 载体 规格 价格
G108540 人 TNFSF13 (NM_001198624) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TNFSF13 (NM_003808) cDNA克隆 transcript variant alpha
人 TNFSF13 (NM_172087) cDNA克隆 transcript variant beta
人 TNFSF13 (NM_001198622) cDNA克隆 transcript variant delta
人 TNFSF13 (NM_001198624) cDNA克隆 transcript variant eta
人 TNFSF13 (NM_172088) cDNA克隆 transcript variant gamma
人 TNFSF13 (NM_001198623) cDNA克隆 transcript variant zeta

基因简介

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]

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