人 RNASE1 (NM_198234) cDNA克隆

基本信息

Accession: NM_198234
基因名称: RNASE1
基因别名: RIB1; RNS1
基因描述: Homo sapiens ribonuclease, RNase A family, 1 (pancreatic) (RNASE1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 471 (查看编码区序列)
翻译后氨基酸长度: 156 (查看氨基酸序列)
Transcript Variant: This variant (2) contains an additional segment in the 5' UTR compared to variant 4. Variants 1, 2, 3 and 4 encode the same protein.

订购信息

产品编号 产品名称 载体 规格 价格
G107738 人 RNASE1 (NM_198234) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RNASE1 (NM_198235) cDNA克隆 transcript variant 1
人 RNASE1 (NM_198234) cDNA克隆 transcript variant 2
人 RNASE1 (NM_198232) cDNA克隆 transcript variant 3
人 RNASE1 (NM_002933) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

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