人 PLA2G2A (NM_001161728) cDNA克隆

基本信息

Accession: NM_001161728
基因名称: PLA2G2A
基因别名: MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2
基因描述: Homo sapiens phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A), transcript variant 3, mRNA.
种属: Human
CDS区长度: 435 (查看编码区序列)
翻译后氨基酸长度: 144 (查看氨基酸序列)
Transcript Variant: This variant (3) is missing one of the 5' non-coding exons compared to variant 1. Variants 1-4 encode the same protein.

订购信息

产品编号 产品名称 载体 规格 价格
G107677 人 PLA2G2A (NM_001161728) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PLA2G2A (NM_000300) cDNA克隆 transcript variant 1
人 PLA2G2A (NM_001161727) cDNA克隆 transcript variant 2
人 PLA2G2A (NM_001161728) cDNA克隆 transcript variant 3
人 PLA2G2A (NM_001161729) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]

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