人 EGLN2 (NM_053046) cDNA克隆

基本信息

Accession: NM_053046
基因名称: EGLN2
基因别名: EIT6; PHD1; HPH-1; HPH-3; HIFPH1; HIF-PH1
基因描述: Homo sapiens egl-9 family hypoxia-inducible factor 2 (EGLN2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1224 (查看编码区序列)
翻译后氨基酸长度: 407 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Both variants 1 and 3 utilize alternative start codons that result in expression of two isoforms known as PHD1p43 and PHD1p40.

订购信息

产品编号 产品名称 载体 规格 价格
G107536 人 EGLN2 (NM_053046) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 EGLN2 (NM_053046) cDNA克隆 transcript variant 1
人 EGLN2 (NM_080732) cDNA克隆 transcript variant 3

基因简介

The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011]

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