人 PHPT1 (NM_001135861) cDNA克隆

Accession: NM_001135861
基因名称: PHPT1
基因别名: PHP14; CGI-202; HSPC141
基因描述: Homo sapiens phosphohistidine phosphatase 1 (PHPT1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 375 (查看编码区序列)
翻译后氨基酸长度: 124 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region and includes an alternate exon in the 3' coding region, compared to variant 4. This results in a frameshift and an early stop codon. It encodes isoform 2, which is shorter and has a distinct C-terminus, compared to isoform 4.
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G107531 人 PHPT1 (NM_001135861) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]