人 TANK (NM_001199135) cDNA克隆

基本信息

Accession: NM_001199135
基因名称: TANK
基因别名: ITRAF; TRAF2; I-TRAF
基因描述: Homo sapiens TRAF family member-associated NFKB activator (TANK), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1278 (查看编码区序列)
翻译后氨基酸长度: 425 (查看氨基酸序列)
Transcript Variant: This variant (3) has an alternate 5' UTR exon compared to variant 1. Variants 1 and 2 encode the same isoform (a).

订购信息

产品编号 产品名称 载体 规格 价格
G107502 人 TANK (NM_001199135) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TANK (NM_004180) cDNA克隆 transcript variant 1
人 TANK (NM_133484) cDNA克隆 transcript variant 2
人 TANK (NM_001199135) cDNA克隆 transcript variant 3

基因简介

The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

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