人 INVS (NM_014425) cDNA克隆

Accession: NM_014425
基因名称: INVS
基因别名: INV; NPH2; NPHP2
基因描述: Homo sapiens inversin (INVS), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3198 (查看编码区序列)
翻译后氨基酸长度: 1065 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (a).
产品编号 产品名称 载体 规格 价格
G107390 人 INVS (NM_014425) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2012]