人 DBN1 (NM_080881) cDNA克隆

Accession: NM_080881
基因名称: DBN1
基因别名: D0S117E
基因描述: Homo sapiens drebrin 1 (DBN1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1956 (查看编码区序列)
翻译后氨基酸长度: 651 (查看氨基酸序列)
Transcript Variant: This variant (2) encodes isoform b and has a different 5' UTR and 5' coding sequence as compared to transcript variant 1. The first 31 amino acids of this isoform differ from the first 29 amino acids of isoform a.
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G107144 人 DBN1 (NM_080881) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]