人 EEF1D (NM_001960) cDNA克隆

基本信息

Accession: NM_001960
基因名称: EEF1D
基因别名: EF1D; EF-1D; FP1047
基因描述: Homo sapiens eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) (EEF1D), transcript variant 2, mRNA.
种属: Human
CDS区长度: 846 (查看编码区序列)
翻译后氨基酸长度: 281 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Variants 2, 5, and 6 encode the same isoform (2).

订购信息

产品编号 产品名称 载体 规格 价格
G107135 人 EEF1D (NM_001960) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 EEF1D (NM_032378) cDNA克隆 transcript variant 1
人 EEF1D (NM_001960) cDNA克隆 transcript variant 2
人 EEF1D (NM_001130053) cDNA克隆 transcript variant 3
人 EEF1D (NM_001130055) cDNA克隆 transcript variant 5
人 EEF1D (NM_001130057) cDNA克隆 transcript variant 6
人 EEF1D (NM_001130056) cDNA克隆 transcript variant 7
人 EEF1D (NM_001195203) cDNA克隆 transcript variant 8

基因简介

This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010]

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