人 PKM (NM_182470) cDNA克隆

基本信息

Accession: NM_182470
基因名称: PKM
基因别名: PK3; TCB; OIP3; PKM2; CTHBP; THBP1
基因描述: Homo sapiens pyruvate kinase, muscle (PKM), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1596 (查看编码区序列)
翻译后氨基酸长度: 531 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 4. The resulting isoform (b, also called M1) is shorter at the N-terminus compared to isoform c.

订购信息

产品编号 产品名称 载体 规格 价格
G106964 人 PKM (NM_182470) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PKM (NM_002654) cDNA克隆 transcript variant 1
人 PKM (NM_182470) cDNA克隆 transcript variant 2
人 PKM (NM_182471) cDNA克隆 transcript variant 3
人 PKM (NM_001206796) cDNA克隆 transcript variant 4
人 PKM (NM_001206797) cDNA克隆 transcript variant 5
人 PKM (NM_001206798) cDNA克隆 transcript variant 6
人 PKM (NM_001206799) cDNA克隆 transcript variant 7

基因简介

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]

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