人 DDC (NM_001242886) cDNA克隆

基本信息

Accession: NM_001242886
基因名称: DDC
基因别名: AADC
基因描述: Homo sapiens dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1329 (查看编码区序列)
翻译后氨基酸长度: 442 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an in-frame coding exon, compared to variant 2. The resulting isoform (2) lacks an internal segment, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G106829 人 DDC (NM_001242886) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 DDC (NM_001082971) cDNA克隆 transcript variant 1
人 DDC (NM_000790) cDNA克隆 transcript variant 2
人 DDC (NM_001242886) cDNA克隆 transcript variant 3
人 DDC (NM_001242887) cDNA克隆 transcript variant 4
人 DDC (NM_001242888) cDNA克隆 transcript variant 5
人 DDC (NM_001242889) cDNA克隆 transcript variant 6
人 DDC (NM_001242890) cDNA克隆 transcript variant 7

基因简介

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]

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