人 FLI1 (NM_001271010) cDNA克隆

Accession: NM_001271010
基因名称: FLI1
基因别名: EWSR2; SIC-1
基因描述: Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1161 (查看编码区序列)
翻译后氨基酸长度: 386 (查看氨基酸序列)
Transcript Variant: This variant (3) contains a distinct 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct and shorter N-terminus, compared to isoform 1.
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G106748 人 FLI1 (NM_001271010) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]