人 AADAT (NM_001286683) cDNA克隆

基本信息

Accession: NM_001286683
基因名称: AADAT
基因别名: KAT2; KATII
基因描述: Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1278 (查看编码区序列)
翻译后氨基酸长度: 425 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of the first coding exon compared to variant 3. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 1, 2, and 4 all encode the same isoform (b).

订购信息

产品编号 产品名称 载体 规格 价格
G106620 人 AADAT (NM_001286683) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 AADAT (NM_016228) cDNA克隆 transcript variant 1
人 AADAT (NM_182662) cDNA克隆 transcript variant 2
人 AADAT (NM_001286682) cDNA克隆 transcript variant 3
人 AADAT (NM_001286683) cDNA克隆 transcript variant 4

基因简介

This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

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