人 P2RX4 (NM_001261398) cDNA克隆

Accession: NM_001261398
基因名称: P2RX4
基因别名: P2X4; P2X4R
基因描述: Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1026 (查看编码区序列)
翻译后氨基酸长度: 341 (查看氨基酸序列)
Transcript Variant: This variant (6) lacks an in-frame exon in the 5' coding region and a segment in the 3' region, compared to variant 1. The resulting isoform (4) lacks an internal segment and has a shorter and distinct C-terminus, compared to isoform 1.
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G106397 人 P2RX4 (NM_001261398) cDNA克隆 pDONR223 2ug质粒 点击询价

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]