人 PARD6A (NM_001037281) cDNA克隆

基本信息

Accession: NM_001037281
基因名称: PARD6A
基因别名: PAR6; PAR6C; TAX40; PAR-6A; TIP-40; PAR6alpha
基因描述: Homo sapiens par-6 family cell polarity regulator alpha (PARD6A), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1038 (查看编码区序列)
翻译后氨基酸长度: 345 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1, resulting in a protein (isoform 2) that is one amino acid shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G106059 人 PARD6A (NM_001037281) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PARD6A (NM_016948) cDNA克隆 transcript variant 1
人 PARD6A (NM_001037281) cDNA克隆 transcript variant 2

基因简介

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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