人 MEST (NM_002402) cDNA克隆

Accession: NM_002402
基因名称: MEST
基因别名: PEG1
基因描述: Homo sapiens mesoderm specific transcript (MEST), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1008 (查看编码区序列)
翻译后氨基酸长度: 335 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). This isoform (a) is imprinted and expressed only from the paternal allele.
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G105971 人 MEST (NM_002402) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011]