人 KCNIP4 (NM_147182) cDNA克隆

基本信息

Accession: NM_147182
基因名称: KCNIP4
基因别名: CALP; KCHIP4
基因描述: Homo sapiens Kv channel interacting protein 4 (KCNIP4), transcript variant 3, mRNA.
种属: Human
CDS区长度: 567 (查看编码区序列)
翻译后氨基酸长度: 188 (查看氨基酸序列)
Transcript Variant: This variant (3) has an alternate exon which lacks an in-frame start codon, as compared to variant 1. Use of a downstream start codon results in an isoform (3, also known as KCHIP4.3) that has a shorter N-terminus, as compared to isoform 1. Variants 3 and 6 encode the same isoform (3).

订购信息

产品编号 产品名称 载体 规格 价格
G105518 人 KCNIP4 (NM_147182) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 KCNIP4 (NM_025221) cDNA克隆 transcript variant 1
人 KCNIP4 (NM_147181) cDNA克隆 transcript variant 2
人 KCNIP4 (NM_147182) cDNA克隆 transcript variant 3
人 KCNIP4 (NM_147183) cDNA克隆 transcript variant 4
人 KCNIP4 (NM_001035003) cDNA克隆 transcript variant 5
人 KCNIP4 (NM_001035004) cDNA克隆 transcript variant 6

基因简介

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

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