人 PEMT (NM_148172) cDNA克隆

Accession: NM_148172
基因名称: PEMT
基因别名: PNMT; PEAMT; PEMPT; PEMT2
基因描述: Homo sapiens phosphatidylethanolamine N-methyltransferase (PEMT), transcript variant 1, mRNA.
种属: Human
CDS区长度: 711 (查看编码区序列)
翻译后氨基酸长度: 236 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1). Isoform 1 localizes to the endoplasmic reticulum.
产品编号 产品名称 载体 规格 价格
G105471 人 PEMT (NM_148172) cDNA克隆 pDONR223 2ug质粒 点击询价

Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012]