人 IGF2 (NM_001127598) cDNA克隆

基本信息

Accession: NM_001127598
基因名称: IGF2
基因别名: IGF-II; PP9974; C11orf43
基因描述: Homo sapiens insulin-like growth factor 2 (somatomedin A) (IGF2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 711 (查看编码区序列)
翻译后氨基酸长度: 236 (查看氨基酸序列)
Transcript Variant: This variant (3) contains two alternate exons at the 5' end, one non-coding and another coding, compared to variant 1. This results in the use of an upstream AUG (not found in variants 1 and 2) and a longer isoform (2) with a distinct N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G105171 人 IGF2 (NM_001127598) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IGF2 (NM_000612) cDNA克隆 transcript variant 1
人 IGF2 (NM_001007139) cDNA克隆 transcript variant 2
人 IGF2 (NM_001127598) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

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