人 TPD52L1 (NM_001003397) cDNA克隆

基本信息

Accession: NM_001003397
基因名称: TPD52L1
基因别名: D53; hD53
基因描述: Homo sapiens tumor protein D52-like 1 (TPD52L1), transcript variant 4, mRNA.
种属: Human
CDS区长度: 396 (查看编码区序列)
翻译后氨基酸长度: 131 (查看氨基酸序列)
Transcript Variant: This variant (4), also known as hD53L1, lacks two coding exons compared to variant 1, which leads to a translation frameshift. The resulting isoform (4) has a distinct and shorter C-terminus, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G104916 人 TPD52L1 (NM_001003397) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TPD52L1 (NM_003287) cDNA克隆 transcript variant 1
人 TPD52L1 (NM_001003395) cDNA克隆 transcript variant 2
人 TPD52L1 (NM_001003396) cDNA克隆 transcript variant 3
人 TPD52L1 (NM_001003397) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined. [provided by RefSeq, Jul 2008]

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