人 BEX2 (NM_032621) cDNA克隆

基本信息

Accession: NM_032621
基因名称: BEX2
基因别名: BEX1; DJ79P11.1
基因描述: Homo sapiens brain expressed X-linked 2 (BEX2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 387 (查看编码区序列)
翻译后氨基酸长度: 128 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1. Variants 3 and 4 encode the same isoform (3).

订购信息

产品编号 产品名称 载体 规格 价格
G104813 人 BEX2 (NM_032621) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 BEX2 (NM_001168399) cDNA克隆 transcript variant 1
人 BEX2 (NM_001168400) cDNA克隆 transcript variant 2
人 BEX2 (NM_032621) cDNA克隆 transcript variant 3
人 BEX2 (NM_001168401) cDNA克隆 transcript variant 4

基因简介

This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

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