人 RNF40 (NM_001286572) cDNA克隆

Accession: NM_001286572
基因名称: RNF40
基因别名: BRE1B; RBP95; STARING
基因描述: Homo sapiens ring finger protein 40, E3 ubiquitin protein ligase (RNF40), transcript variant 4, mRNA.
种属: Human
CDS区长度: 3006 (查看编码区序列)
翻译后氨基酸长度: 1001 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1 and 4 both encode the same isoform (1).
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G104655 人 RNF40 (NM_001286572) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]