人 USP5 (NM_003481) cDNA克隆

基本信息

Accession: NM_003481
基因名称: USP5
基因别名: ISOT
基因描述: Homo sapiens ubiquitin specific peptidase 5 (isopeptidase T) (USP5), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2508 (查看编码区序列)
翻译后氨基酸长度: 835 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 2).

订购信息

产品编号 产品名称 载体 规格 价格
G104444 人 USP5 (NM_003481) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 USP5 (NM_001098536) cDNA克隆 transcript variant 1
人 USP5 (NM_003481) cDNA克隆 transcript variant 2

基因简介

Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010]

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