人 GPR56 (NM_001145774) cDNA克隆

基本信息

Accession: NM_001145774
基因名称: GPR56
基因别名: BFPP; TM7LN4; TM7XN1
基因描述: Homo sapiens G protein-coupled receptor 56 (GPR56), transcript variant 7, mRNA.
种属: Human
CDS区长度: 2064 (查看编码区序列)
翻译后氨基酸长度: 687 (查看氨基酸序列)
Transcript Variant: This variant (7) represents use of an alternate promoter, differs in the 5' UTR, and uses an alternate splice acceptor site in the central coding region, compared to variant 4. The resulting isoform (b) lacks an internal 6 aa segment, compared to isoform a. Variants 2, 3, 5, 6, and 7 encode the same isoform.

订购信息

产品编号 产品名称 载体 规格 价格
G104282 人 GPR56 (NM_001145774) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GPR56 (NM_005682) cDNA克隆 transcript variant 1
人 GPR56 (NM_201524) cDNA克隆 transcript variant 2
人 GPR56 (NM_201525) cDNA克隆 transcript variant 3
人 GPR56 (NM_001145771) cDNA克隆 transcript variant 4
人 GPR56 (NM_001145770) cDNA克隆 transcript variant 5
人 GPR56 (NM_001145772) cDNA克隆 transcript variant 6
人 GPR56 (NM_001145774) cDNA克隆 transcript variant 7
人 GPR56 (NM_001145773) cDNA克隆 transcript variant 8

基因简介

This gene encodes a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

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