人 PCK2 (NM_001018073) cDNA克隆

Accession: NM_001018073
基因名称: PCK2
基因别名: PEPCK; PEPCK2; PEPCK-M
基因描述: Homo sapiens phosphoenolpyruvate carboxykinase 2 (mitochondrial) (PCK2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1326 (查看编码区序列)
翻译后氨基酸长度: 441 (查看氨基酸序列)
Transcript Variant: This variant (2) contains an alternate, in-frame segment in the 3' coding region, compared to variant 1. This variant is supported by mRNAs but experimental evidence for its protein product is not available. The predicted isoform (2) encoded by this variant has a distinct and shorter C-terminus, compared to isoform 1.
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G104203 人 PCK2 (NM_001018073) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]