人 NCF2 (NM_001190794) cDNA克隆

基本信息

Accession: NM_001190794
基因名称: NCF2
基因别名: NCF-2; NOXA2; P67PHOX; P67-PHOX
基因描述: Homo sapiens neutrophil cytosolic factor 2 (NCF2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1446 (查看编码区序列)
翻译后氨基酸长度: 481 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an in-frame exon in the CDS, as compared to variant 1. The resulting isoform (2) lacks an internal segment, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G104053 人 NCF2 (NM_001190794) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NCF2 (NM_000433) cDNA克隆 transcript variant 1
人 NCF2 (NM_001127651) cDNA克隆 transcript variant 2
人 NCF2 (NM_001190794) cDNA克隆 transcript variant 3
人 NCF2 (NM_001190789) cDNA克隆 transcript variant 4

基因简介

This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]

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