人 EIF2B3 (NM_020365) cDNA克隆

Accession: NM_020365
基因名称: EIF2B3
基因别名: EIF-2B; EIF2Bgamma
基因描述: Homo sapiens eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa (EIF2B3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1359 (查看编码区序列)
翻译后氨基酸长度: 452 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (1).
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G103922 人 EIF2B3 (NM_020365) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]