人 ARMC10 (NM_001161013) cDNA克隆

Accession: NM_001161013
基因名称: ARMC10
基因别名: SVH; PNAS112; PNAS-112; PSEC0198
基因描述: Homo sapiens armadillo repeat containing 10 (ARMC10), transcript variant F, mRNA.
种属: Human
CDS区长度: 678 (查看编码区序列)
翻译后氨基酸长度: 225 (查看氨基酸序列)
Transcript Variant: This variant (F) lacks three in-frame exons in the coding region compared to variant A. This results in a shorter protein (isoform f) compared to isoform a.
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G103806 人 ARMC10 (NM_001161013) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]