人 PMEPA1 (NM_001255976) cDNA克隆

Accession: NM_001255976
基因名称: PMEPA1
基因别名: STAG1; TMEPAI
基因描述: Homo sapiens prostate transmembrane protein, androgen induced 1 (PMEPA1), transcript variant 5, mRNA.
种属: Human
CDS区长度: 780 (查看编码区序列)
翻译后氨基酸长度: 259 (查看氨基酸序列)
Transcript Variant: This variant (5) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (d) is shorter and has a distinct N-terminus, compared to isoform a.
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G103585 人 PMEPA1 (NM_001255976) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]