人 GSTZ1 (NM_145871) cDNA克隆

Accession: NM_145871
基因名称: GSTZ1
基因别名: MAI; MAAI; GSTZ1-1
基因描述: Homo sapiens glutathione S-transferase zeta 1 (GSTZ1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 525 (查看编码区序列)
翻译后氨基酸长度: 174 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.
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G103486 人 GSTZ1 (NM_145871) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms. [provided by RefSeq, Jul 2008]