人 TSPO (NM_000714) cDNA克隆

Accession: NM_000714
基因名称: TSPO
基因别名: DBI; IBP; MBR; PBR; PBS; BPBS; BZRP; PKBS; PTBR; mDRC; pk18
基因描述: Homo sapiens translocator protein (18kDa) (TSPO), transcript variant PBR, mRNA.
种属: Human
CDS区长度: 510 (查看编码区序列)
翻译后氨基酸长度: 169 (查看氨基酸序列)
Transcript Variant: This variant (PBR) consists of four exons and encodes the protein PBR.
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G103232 人 TSPO (NM_000714) cDNA克隆 pDONR223 2ug质粒 点击询价

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012]