人 TSC22D1 (NM_006022) cDNA克隆

基本信息

Accession: NM_006022
基因名称: TSC22D1
基因别名: Ptg-2; TSC22; TGFB1I4
基因描述: Homo sapiens TSC22 domain family, member 1 (TSC22D1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 435 (查看编码区序列)
翻译后氨基酸长度: 144 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a large portion of the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2, also known as TSC22D1.2) is significantly shorter and has a distinct N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G103097 人 TSC22D1 (NM_006022) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TSC22D1 (NM_183422) cDNA克隆 transcript variant 1
人 TSC22D1 (NM_006022) cDNA克隆 transcript variant 2
人 TSC22D1 (NM_001243797) cDNA克隆 transcript variant 3
人 TSC22D1 (NM_001243798) cDNA克隆 transcript variant 4
人 TSC22D1 (NM_001243799) cDNA克隆 transcript variant 5

基因简介

This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

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