人 MEF2BNB-MEF2B (NM_005919) cDNA克隆

Accession: NM_005919
基因名称: MEF2BNB-MEF2B
基因别名: MEF2B; LOC729991-MEF2B
基因描述: Homo sapiens MEF2BNB-MEF2B readthrough (MEF2BNB-MEF2B), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1098 (查看编码区序列)
翻译后氨基酸长度: 365 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks two alternate exons in the 5' region and one alternate exon in the 3' region, compared to variant 2. This variant is thought to be protein coding because translation can reinitiate at the downstream AUG, resulting in expression of an isoform of MEF2B (geneID:100271849). Isoform b has a shorter and distinct C-terminus, compared to MEF2A isoform a (NP_001139257.1).
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G102950 人 MEF2BNB-MEF2B (NM_005919) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene represents numerous read-through transcripts that span GeneID:729991 and 100271849. Many read-through transcripts are predicted to be nonsense-mediated decay (NMD) candidates, and are thought to be non-coding. Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG, resulting in expression of at least one isoform of myocyte enhancer factor 2B (MEF2B) from this read-through locus. At least one additional MEF2B variant and isoform can be expressed from a downstream promoter, and is annotated on GeneID:100271849. [provided by RefSeq, Oct 2010]