人 GGCT (NM_001199816) cDNA克隆

基本信息

Accession: NM_001199816
基因名称: GGCT
基因别名: GGC; GCTG; CRF21; C7orf24
基因描述: Homo sapiens gamma-glutamylcyclotransferase (GGCT), transcript variant 3, mRNA.
种属: Human
CDS区长度: 345 (查看编码区序列)
翻译后氨基酸长度: 114 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an exon in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G102936 人 GGCT (NM_001199816) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GGCT (NM_024051) cDNA克隆 transcript variant 1
人 GGCT (NM_001199815) cDNA克隆 transcript variant 2
人 GGCT (NM_001199816) cDNA克隆 transcript variant 3
人 GGCT (NM_001199817) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

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