Protamines are the major DNA-binding proteins in the nucleus of sperm, and package the DNA in a volume less than 5% of a somatic cell nucleus (summarized by Cho et al., 2001 [PubMed 11326282]). See PRM1 (MIM 182880).[supplied by OMIM, Jul 2010]
Accession: | NM_001286358 |
---|---|
基因名称: | PRM2 |
基因别名: | CT94.2 |
基因描述: | Homo sapiens protamine 2 (PRM2), transcript variant 4, mRNA. |
种属: | Human |
CDS区长度: | 372 (查看编码区序列) |
翻译后氨基酸长度: | 123 (查看氨基酸序列) |
Transcript Variant: | This variant (4) uses an alternate splice junction at the 5' end of the last exon compared to variant 1, that causes a frameshift. The resulting isoform (4) has a longer and distinct C-terminus compared to isoform 1. |
人 PRM2 (NM_002762) cDNA克隆 | transcript variant 1 |
人 PRM2 (NM_001286356) cDNA克隆 | transcript variant 2 |
人 PRM2 (NM_001286357) cDNA克隆 | transcript variant 3 |
人 PRM2 (NM_001286358) cDNA克隆 | transcript variant 4 |
人 PRM2 (NM_001286359) cDNA克隆 | transcript variant 5 |
Protamines are the major DNA-binding proteins in the nucleus of sperm, and package the DNA in a volume less than 5% of a somatic cell nucleus (summarized by Cho et al., 2001 [PubMed 11326282]). See PRM1 (MIM 182880).[supplied by OMIM, Jul 2010]