人 PVRL3 (NM_001243288) cDNA克隆

Accession: NM_001243288
基因名称: PVRL3
基因别名: PPR3; PRR3; CD113; PVRR3; CDW113; NECTIN-3
基因描述: Homo sapiens poliovirus receptor-related 3 (PVRL3), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1464 (查看编码区序列)
翻译后氨基酸长度: 487 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, uses a distinct start codon, and has alternate exon structure in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (3) has distinct N- and C-termini and is shorter than isoform 1.
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G102866 人 PVRL3 (NM_001243288) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]