人 WWP2 (NM_001270455) cDNA克隆

Accession: NM_001270455
基因名称: WWP2
基因别名: AIP2; WWp2-like
基因描述: Homo sapiens WW domain containing E3 ubiquitin protein ligase 2 (WWP2), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1008 (查看编码区序列)
翻译后氨基酸长度: 335 (查看氨基酸序列)
Transcript Variant: This variant (6) differs in the 3' UTR, compared to variant 1. The encoded isoform (WWP2-N) has a shorter C-terminus, compared to isoform 1.
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G102601 人 WWP2 (NM_001270455) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10. [provided by RefSeq, Jul 2012]