人 PLIN3 (NM_001164194) cDNA克隆

Accession: NM_001164194
基因名称: PLIN3
基因别名: PP17; TIP47; M6PRBP1
基因描述: Homo sapiens perilipin 3 (PLIN3), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1269 (查看编码区序列)
翻译后氨基酸长度: 422 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1.
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G101894 人 PLIN3 (NM_001164194) cDNA克隆 pDONR223 2ug质粒 点击询价

Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2009]