人 TXNRD2 (NM_001282512) cDNA克隆

Accession: NM_001282512
基因名称: TXNRD2
基因别名: TR; TR3; SELZ; TRXR2; TR-BETA
基因描述: Homo sapiens thioredoxin reductase 2 (TXNRD2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1017 (查看编码区序列)
翻译后氨基酸长度: 338 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks exons in the 3' coding region and uses an alternate 3' terminal exon compared to variant 1. The resulting protein (isoform 2) has a shorter, distinct C-terminus compared to isoform 1 and does not contain selenocysteine.
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G101848 人 TXNRD2 (NM_001282512) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2013]