人 GAK (NM_001286833) cDNA克隆

Accession: NM_001286833
基因名称: GAK
基因别名: DNAJ26; DNAJC26
基因描述: Homo sapiens cyclin G associated kinase (GAK), transcript variant 2, mRNA.
种属: Human
CDS区长度: 3642 (查看编码区序列)
翻译后氨基酸长度: 1213 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame segment in the 5' end compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
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G101753 人 GAK (NM_001286833) cDNA克隆 pDONR223 2ug质粒 点击询价

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]