人 PLEKHA1 (NM_001195608) cDNA克隆

基本信息

Accession: NM_001195608
基因名称: PLEKHA1
基因别名: TAPP1
基因描述: Homo sapiens pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 (PLEKHA1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1005 (查看编码区序列)
翻译后氨基酸长度: 334 (查看氨基酸序列)
Transcript Variant: This variant (3) is shorter at the 5' UTR and includes an alternate exon, which results in a frameshift, compared to variant 1. The resulting isoform (2) has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G101686 人 PLEKHA1 (NM_001195608) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PLEKHA1 (NM_021622) cDNA克隆 transcript variant 1
人 PLEKHA1 (NM_001001974) cDNA克隆 transcript variant 2
人 PLEKHA1 (NM_001195608) cDNA克隆 transcript variant 3

基因简介

This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010]

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