人 TSEN34 (NM_001077446) cDNA克隆

Accession: NM_001077446
基因名称: TSEN34
基因别名: LENG5; PCH2C; SEN34; SEN34L
基因描述: Homo sapiens TSEN34 tRNA splicing endonuclease subunit (TSEN34), transcript variant 2, mRNA.
种属: Human
CDS区长度: 933 (查看编码区序列)
翻译后氨基酸长度: 310 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same isoform (1).
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G101592 人 TSEN34 (NM_001077446) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Oct 2009]