人 LAIR1 (NM_002287) cDNA克隆

Accession: NM_002287
基因名称: LAIR1
基因别名: CD305; LAIR-1
基因描述: Homo sapiens leukocyte-associated immunoglobulin-like receptor 1 (LAIR1), transcript variant a, mRNA.
种属: Human
CDS区长度: 864 (查看编码区序列)
翻译后氨基酸长度: 287 (查看氨基酸序列)
Transcript Variant: This variant (a) is the full-length transcript.
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G101034 人 LAIR1 (NM_002287) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. [provided by RefSeq, Jul 2008]