人 PPP1R1B (NM_001242464) cDNA克隆

Accession: NM_001242464
基因名称: PPP1R1B
基因别名: DARPP32; DARPP-32
基因描述: Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 1B (PPP1R1B), transcript variant 3, mRNA.
种属: Human
CDS区长度: 507 (查看编码区序列)
翻译后氨基酸长度: 168 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Variants 2 and 3 encode isoform 2
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G100341 人 PPP1R1B (NM_001242464) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]